Xi Lab

 

发表的部分论文  [PubMed]

 Last update: 20170225

2017年

Shi, Jing, Na-Nv Liu, Yan-Tao Yang, and Xu-Guang Xi. "Purification and enzymatic characterization of Gallus gallus BLM helicase." The Journal of Biochemistry (2017).

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A Helical Bundle in the N-terminal Domain of the BLM Helicase Mediates Dimer and Potentially Hexamer Formation.

Shi J, Chen WF, Zhang B, Fan SH, Ai X, Liu NN, Rety S, Xi XG. J Biol Chem. 2017 Feb 22. pii: jbc.M116.761510. doi: 10.1074/jbc.M116.761510. [Epub ahead of print]

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Wei, Xiao-Bin, Bo Zhang, Nicolas Bazeille, Ying Yu, Na-Nv Liu, Brigitte René, Olivier Mauffret, and Xu-Guang Xi. "A 3′-5′ exonuclease activity embedded in the helicase core domain of Candida albicans Pif1 helicase." Scientific Reports 7 (2017): 42865.

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2016年

Zhang, B., Wu, W.-Q., Liu, N.-N., Duan, X.-L., Li, M., Dou, S.-X., Hou, X.-M. and Xi, X.-G. (2016) G-quadruplex and G-rich sequence

stimulate Pif1p-catalyzed downstream duplex DNA unwinding through reducing waiting time at ss/dsDNA junction.

Nucleic Acids Res., 10.1093/nar/gkw1669.（IF：9.202）

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Wei QIN, Nicolas BAZEILLE, Etienne HENRY, Bo ZHANG, Eric DEPREZ,Xu-Guang Xi*. Mechanistic insight into cadmium-induced inactivation of the Bloom protein. Scientific Reports, 2016, accepted.（IF：5.578）

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Jing-Hua Li, Wen-Xia Lin, Bo Zhang, Da-Guan Nong, Hai-Peng Ju, Jian-Bing Ma,Chun-Hua Xu, Fang-Fu Ye,Xu-Guang Xi , Ming Li, Ying Lu and Shuo-Xing Dou. Pif1 is a force-regulated helicase. Nucleic Acids Research , 2016 Apr 20. doi: 10.1093/nar/gkw295 [Epub ahead of print]（IF：9.202）

 

Wei-Fei Chen, Yang-Xue Dai, Xiao-Lei Duan, Na-Nv Liu, Wei Shi, Na Li, Ming Li, Shou-Xing Dou, Yu-Hui Dong, Stephane Rety, Xu-Guang Xi*. Crystal structures of the BsPif1 helicase revealthat a major movementof the 2B SH3 domain is required for DNA unwinding. Nucleic Acids Research, 2016, 44 (6): 2949–2961.（IF：9.202）

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2015年

Na-Nv Liu, Xiao-Lei Duan, Xia Ai, Yan-Tao Yang, Ming Li, Shuo-Xing Dou,Stephane Rety, Eric Deprez and Xu-Guang Xi *. The Bacteroides sp. 3 1 23 Pif1 protein is a multifunctional helicase. Nucleic Acids Research. 2015, 43 (18): 8942-8954.（IF：9.202）

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Wen-Qiang Wu, Xi-Miao Hou, Ming Li, Shuo-Xing Dou and Xu-Guang Xi *. BLM unfolds G-quadruplexes in different structural environments through different mechanisms. Nucleic Acids Research. 2015, 43(9), 4614-4626.（IF：9.202）

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Xiao-Lei Duan, Na-Nv Liu, Yan-Tao Yang, Hai-Hong Li, Ming Li, Shuo-Xing Dou, and Xu-Guang Xi*.  G-Quadruplexes Significantly Stimulate Pif1 Helicase-catalyzed Duplex DNA Unwinding. The Journal of Biological Chemistry, 2015, 290(16):7722-7735.（IF：4.573）

 

Wang, Shuang; Qin, Wei; Li, Jing-Hua; Lu, Ying; Lu, Ke-Yu; Nong, Da-Guan; Dou, Shuo-Xing; Xu, Chun-Hua;Xu-Guang Xi*.; Li, Ming. Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase. Nucleic Acids Research, 2015, 43(7), 3736–3746.（IF：9.112）

 

Hou X., Wu W., Duan X., Liu N., Li H., Fu J., Dou S., Li M. and Xu-Guang Xi*. Molecular mechanism of G-quadruplex unwinding helicase: sequential and repetitive unfolding of G-quadruplex by Pif1 helicase. Biochemical Journal. 2015, 466:189-199.（IF：4.396）

 

2014年

Wei Qin, Na-Nv Liu, Lijun Wang, Min Zhou, Hua Ren, Elisabeth Bugnard, Jie-Lin Liu, Lin-Hu Zhang, Jeremie Vendôme, Jin-Shan Hu, Xu-Guang Xi*. Characterization of Biochemical Properties of Bacillus subtilis RecQ Helicase, Journal of Bacteriology, 2014, 24(196): 4216-4228.（IF：2.808）

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2013年

Li, Wei; Hou, Xi-Miao; Wang, Peng-Ye;Xu-Guang Xi*; Li, Ming. Direct Measurement of Sequential Folding Pathway and Energy Landscape of Human Telomeric G-quadruplex Structures. JACS, 2013, 17(135): 6423 – 6426.（IF：11.444）

 

2012年

DING XiuYan, XU YaNan, LI Wei, WANG PengYe, Xu-Guang Xi*, DOU ShuoXing. Kinetic study of the DNA annealing properties of RECQ5β helicase. Chinese Science Bulletin, 2012, 57(11): 1280-1287. （ IF：1.579）

 

Xu YN, Bazeille N, Ding XY, Lu XM, Wang PY, Bugnard E, Grondin V, Dou SX, Xi XG. Multimeric BLM is dissociated upon ATP hydrolysis and functions as monomers in resolving DNA structures. Nucleic Acids Research, 2012, 40 (19):9802-14.（IF：9.112）